Foodborne pathogen control is a multi-factorial issue that concerns the whole poultry production chain, from farm to fork. It has led the industry to develop integrated prevention programs that are implemented from the feed mill to the farm building. A new nutritional tool can be integrated within a comprehensive Salmonella control strategy. The European Union has authorized the live yeast probiotic strain S. c. boulardii CNCM I-1079 as a feed additive for the reduction of carcass contamination by Salmonella spp. in broiler chickens.