Investigating how maternal nutrition can impact offspring

By Jane Byrne

- Last updated on GMT

© GettyImages/FluxFactory
© GettyImages/FluxFactory

Related tags Metabolism epigenetic

A US animal scientist, based at the University of Connecticut, will examine how over-feeding of the mother during gestation causes epigenetic changes in offspring liver that ultimately affect growth, metabolism, and inflammation.

Associate professor of animal science at the College of Agriculture, Health and Natural Resources, Kristen Govoni, has received a US$25K grant via that university’s Research Excellence Program (REP) to investigate the effects of maternal nutrition on offspring health.

The REP provides seed funding to fuel innovative research, scholarship, and creative projects.

We know that poor nutrition during gestation causes reduced growth, increased fat deposition, and metabolic dysregulation in offspring. This REP award will allow us to further explore the mechanisms that contribute to programming in the fetus and with the long-term goal of identifying methods of early intervention to prevent and/or decreased metabolic disease later in life,” ​said Govoni.

She will be using sheep as a model for the study.

Fetal programming

Challenges for a mother during pregnancy can positively or negatively contribute to fetal programming, which leads to changes that can alter later development of the offspring, said the researcher.

There is recent evidence that suggests such effects can extend to subsequent generations as well, even if the nutrition is normal for the first generation of offspring.

In conjunction with the lab of Sarah Reed, associate professor in the Department of Animal Science, Govoni is also evaluating the effects of maternal dietary changes on offspring muscle growth, oxidative stress, and inflammation. That research is funded by the US Department of Agriculture (USDA).

Combined, she said, the two studies should paint a complete picture of the impacts of both over- and under-feeding during pregnancy on subsequent offspring growth and metabolism.

Related news

Show more

Related products

show more

A pioneer and leader in microbial fermentation

A pioneer and leader in microbial fermentation

Content provided by Lallemand Animal Nutrition | 05-Dec-2023 | Business Advice

For over 100 years we've been producing yeast and bacteria for a variety of markets, Lallemand has perfected the art of fermentation. As primary microorganism...

YeaMOS T—Special Yeast Cell Wall for Mycotoxin Bin

YeaMOS T—Special Yeast Cell Wall for Mycotoxin Bin

Content provided by Angel Yeast - animal nutrition | 11-Oct-2023 | Research Study

YeaMOS T, which has been strengthened the advantages of adsorption sites in the yeast cell wall and possesses excellent adsorption effect in the toxins.

Animal AgTech San Francisco, March 18-19, 2024

Animal AgTech San Francisco, March 18-19, 2024

Content provided by Animal AgTech Innovation Summit | 15-Aug-2023 | White Paper

Animal AgTech is the go-to meeting place for the meat and dairy supply chain to accelerate action for animal health and environmental stewardship.

Related suppliers